SPORTS ROUNDERS

Daily MLB research board · Updated Sep 22, 1:13 AM CT

MLB best bets, predictions and odds for Tuesday, September 22

Every posted game is screened below so bettors can start research early. “Prediction” describes the current market view; only a separately labeled Official Play is a Sports Rounders release.

Free pick alerts

Get the next MLB pick and playable price before kickoff.

When a selection clears our process, we email the exact pick, sportsbook price, and betting limit. If nothing qualifies, we send the honest pass. Free, no card required.

Full slate

16 games researched

01
Rays vs Yankees12:05 PM CT · Nick Martinez vs. Carlos Rodón · Yankee Stadium

New York Yankees hold the stronger current market position at a no-vig estimate of 54.2%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Yankees are the current prediction to win
02
Rays vs Yankees6:05 PM CT · Drew Rasmussen vs. Max Fried · Yankee Stadium

New York Yankees hold the stronger current market position at a no-vig estimate of 54.2%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Yankees are the current prediction to win
03
Jays vs Orioles5:35 PM CT · Max Scherzer vs. Chris Bassitt · Oriole Park at Camden Yards

Baltimore Orioles hold the stronger current market position at a no-vig estimate of 52.2%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Orioles are the current prediction to win
04
Nationals vs Tigers5:40 PM CT · Jackson Kent vs. Drew Anderson · Comerica Park

Detroit Tigers hold the stronger current market position at a no-vig estimate of 59.1%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Tigers are the current prediction to win
05
Cardinals vs Pirates5:40 PM CT · Andre Pallante vs. Jared Jones · PNC Park

Pittsburgh Pirates hold the stronger current market position at a no-vig estimate of 57.7%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Pirates are the current prediction to win
06
Brewers vs Phillies5:40 PM CT · Dustin May vs. Zack Wheeler · Citizens Bank Park

Philadelphia Phillies hold the stronger current market position at a no-vig estimate of 56%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Phillies are the current prediction to win
07
Guardians vs Sox5:45 PM CT · Parker Messick vs. Payton Tolle · Fenway Park

Boston Red Sox hold the stronger current market position at a no-vig estimate of 54%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Sox are the current prediction to win
08
Reds vs Braves6:15 PM CT · Brandon Williamson vs. JR Ritchie · Truist Park

Atlanta Braves hold the stronger current market position at a no-vig estimate of 62.6%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Braves are the current prediction to win
09
Sox vs Royals6:40 PM CT · Anthony Kay vs. Daniel Lynch IV · Kauffman Stadium

Chicago White Sox hold the stronger current market position at a no-vig estimate of 52.1%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Sox are the current prediction to win
10
Marlins vs Cubs6:40 PM CT · Janson Junk vs. TBD · Wrigley Field

Chicago Cubs hold the stronger current market position at a no-vig estimate of 65.7%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Cubs are the current prediction to win
11
Mets vs Rangers7:05 PM CT · Sean Manaea vs. MacKenzie Gore · Globe Life Field

Texas Rangers hold the stronger current market position at a no-vig estimate of 56.6%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Rangers are the current prediction to win
12
Diamondbacks vs Rockies7:40 PM CT · Michael Soroka vs. Kyle Freeland · Coors Field

Arizona Diamondbacks hold the stronger current market position at a no-vig estimate of 63.1%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Diamondbacks are the current prediction to win
13
Angels vs Athletics8:40 PM CT · Yusei Kikuchi vs. Brady Basso · Sutter Health Park

Athletics hold the stronger current market position at a no-vig estimate of 50.6%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Athletics are the current prediction to win
14
Astros vs Mariners8:40 PM CT · Cristian Javier vs. Logan Gilbert · T-Mobile Park

Seattle Mariners hold the stronger current market position at a no-vig estimate of 56.9%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Mariners are the current prediction to win
15
Twins vs Giants8:45 PM CT · Taj Bradley vs. Anthony Molina · Oracle Park

Minnesota Twins hold the stronger current market position at a no-vig estimate of 54.7%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Twins are the current prediction to win
16
Padres vs Dodgers9:10 PM CT · Michael King vs. TBD · UNIQLO Field at Dodger Stadium

Los Angeles Dodgers hold the stronger current market position at a no-vig estimate of 52.4%. This is a matchup lean, not a qualified Sports Rounders play; the available price still determines whether any wager has value.

Dodgers are the current prediction to win