NFL · Week 1 · September 13, 2026
Arizona Cardinals vs. Los Angeles Chargers prediction, odds and preview
Current market, injury report, venue, weather and decision context for 3:25 PM CT. Data updates as providers post changes.
Arizona Cardinals0-0 · +10.5 (-110)+440FanDuel
Los Angeles Chargers0-0 · -10 (+100)-550DraftKingsCurrent market snapshot
Los Angeles Chargers are favored by 10
The best displayed moneylines are Arizona Cardinals +440 and Los Angeles Chargers -550. After removing the paired-market hold, that implies roughly 18.0% versus 82.0%. This is not an independent model probability.
- Consensus spread
- Los Angeles Chargers -10
- Consensus total
- 47.5
- Model status
- Coverage only
Game environment
Venue, surface and weather
- Venue
- SoFi Stadium
- Location
- Inglewood, CA
- Surface / roof
- Artificial turf · Outdoor
- Forecast
- Forecast pending
Price context
Two-sided markets
- Moneyline
- Cardinals +440 · Chargers -550
- Spread prices
- +10.5 (-110) · -10 (+100)
- No-vig market
- Cardinals 18.0% · Chargers 82.0%
- Last page update
- 4:46 PM CT
Availability report
Injuries and player status
Statuses can change quickly. Recheck inactive lists and credible team reporting before kickoff.
Los Angeles Chargers
- Kyle Kennard LBInjured Reserve · Undisclosed
- Sincere Brown WRInjured Reserve · Undisclosed
- Dalevon Campbell WRInjured Reserve · Leg
- Isaiah World OTout · Knee
- Keaton Mitchell RBquestionable · Undisclosed
Arizona Cardinals
- Jeremiyah Love RBquestionable · Ankle
- Josh Minkins SInjured Reserve · Undisclosed
- Zachary Carter DTInjured Reserve · Knee
- Will Johnson CBquestionable · Lower Body
- Tip Reiman TEout · Ankle
Deep-dive checklist
What still decides whether the number is playable
Quarterback and skill availability
Confirm the starting quarterback, mobility and throwing health, protection changes, receiver roles and expected snap limits.
Trenches in both directions
Measure pass protection versus pressure, run blocking versus front strength, injuries, continuity and likely game-script leverage.
Efficiency and explosiveness
Separate sustainable early-down success and EPA from turnovers, short fields, broken plays and red-zone variance.
Coverage and matchup usage
Evaluate outside, slot, tight-end and running-back receiving roles against the opponent’s coverage structure and personnel.
Coaching, pace and special teams
Account for fourth-down decisions, neutral pace, pass rate, kicking, punting, returns and field-position effects.
Travel, rest and weather
Verify body-clock travel, short weeks, altitude, surface, roof, wind and precipitation at the actual kickoff window.
Sports Rounders NFL policy
Research page, not an Official Play.
The market favorite, public narrative or injury list cannot manufacture an edge. NFL recommendations remain unavailable until a distinct NFL model and prospective validation gate exist.
Los Angeles Chargers -10
Key-number movement through 3, 6, 7, 10 and 14 can materially change value.
47.5 points
Pace, neutral pass rate, explosive plays, red-zone efficiency, weather and injuries require a separate scoring forecast.
No customer pick
This page will never silently turn market consensus into a proprietary recommendation.
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