NFL · Week 5 · October 11, 2026
Detroit Lions vs. Arizona Cardinals prediction, odds and preview
Current market, injury report, venue, weather and decision context for 3:25 PM CT. Data updates as providers post changes.
Detroit Lions3-2 · -20.5 (-120)-240BetRivers
Arizona Cardinals1-4 · +23.5 (-115)+210BetMGMCurrent market snapshot
Detroit Lions are favored by 22
BetMGM lists Detroit Lions -250 and Arizona Cardinals +210. After removing that single book’s hold, the market implies roughly 68.9% versus 31.1%. This is not an independent model probability.
- Consensus spread
- Detroit Lions -22
- Consensus total
- 65.5
- Model status
- Live release
Live research status
What changed—and what is verified
- Active model
- SR-NFL-0.2 Version stamped on releases
- Data refreshed
- Oct 11, 5:52 PM CT Central time
- Books reporting
- Live feed Approved U.S. books only
- Page type
- Prediction Not an Official Play unless labeled
- 01Schedule and kickoffOctober 11, 2026 · 3:25 PM CT
- 02Moneyline, spread and totalAll three same-book market pairs are attached.
- 03Injury and availability feedThe matchup injury feed is still pending.
- 04Environment and decisionIndoor game · Official Plays publish separately after every gate clears.
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Final result and recap
Detroit Lions 45, Arizona Cardinals 21
Detroit Lions won by 24 points in a game that produced 66 total points. The pregame market favorite won outright. The permanent Official Play ledger, rather than this public preview, determines any graded betting result.
- Pregame market call
- Detroit Lions
- Closing spread reference
- Detroit Lions -22
- Closing total reference
- 65.5
Matchup at a glance
The essential game context
- Kickoff
- 3:25 PM CT October 11, 2026
- Week
- 5 Regular season
- Broadcast
- Fox Check local listings
- Setting
- Indoor Grass
- Books reporting
- TBD Connected US market feed
- Availability flags
- Pending Position review pending
Game environment
Venue, surface and weather
- Venue
- State Farm Stadium
- Location
- Glendale, AZ
- Surface / roof
- Grass · Indoor
- Forecast
- Indoor game
Price context
Two-sided markets
- Best displayed moneyline
- Lions -240 · Cardinals +210
- Best displayed spreads
- -20.5 (-120) · +23.5 (-115)
- Same-book no-vig market
- Lions 68.9% · Cardinals 31.1%
- Market feed update
- 8:00 PM CT
Same-book market board
Line, price and source stay together
Paired prices below come from one sportsbook at one market snapshot. Best displayed prices may be better, but can come from different books.
What the market is saying
Implied score and key-number context
These are derived from the consensus spread and total. They summarize the market; they are not Sports Rounders projections.
Sports Rounders matchup analysis
How the number, availability and game environment fit together
Detroit Lions are the current market favorite at Detroit Lions -22. The spread-total combination implies approximately Detroit Lions 43.8 and Arizona Cardinals 21.8. 0 players appear on the connected availability report, including 0 offensive skill or line flags and 0 defensive flags.
The current total is 65.5, classified as higher total. The spread sits 8.0 from 14, so even a half-point move can matter when it crosses an NFL key number. The listed game environment is Indoor game. Those pieces must be evaluated together with quarterback and trench availability before the exact price can qualify.
Game-specific model review
What the current run actually checked
No fresh, frozen game-specific model review is available for this matchup. The general checklist below describes work to do; it is not proof that the work was completed.
Current-season form
How both teams have performed this season
Through 5 Detroit Lions games and 6 Arizona Cardinals games in the 2026 regular season. These are descriptive team totals, not opponent-adjusted efficiency or a stand-alone edge.
- Points scored per game
- DET 32.8 · ARI 21.0
- Net passing yards per game
- DET 279.6 · ARI 211.0
- Rushing yards per game
- DET 114.2 · ARI 96.3
- Yards per pass attempt
- DET 7.8 · ARI 5.7
- Yards per rush attempt
- DET 4.4 · ARI 3.7
- Third-down conversion
- DET 37.3% · ARI 39.3%
- Defensive sacks per game
- DET 4.0 · ARI 2.3
- Turnover differential
- DET 4 · ARI 2
Source: ESPN Detroit Lions team statistics and ESPN Arizona Cardinals team statistics. This is supplemental research; the frozen model run above still uses its stated inputs and is not automatically recalibrated by this table.
Availability report
Injuries and player status
Statuses can change quickly. Recheck inactive lists and credible team reporting before kickoff. A blank feed is treated as unknown—not healthy.
The connected feed has not posted a matchup injury report yet. Missing data is not treated as healthy availability.
Deep-dive checklist
What still decides whether the number is playable
Quarterback and skill availability
Confirm the starting quarterback, mobility and throwing health, protection changes, receiver roles and expected snap limits.
Trenches in both directions
Measure pass protection versus pressure, run blocking versus front strength, injuries, continuity and likely game-script leverage.
Efficiency and explosiveness
Separate sustainable early-down success and EPA from turnovers, short fields, broken plays and red-zone variance.
Coverage and matchup usage
Evaluate outside, slot, tight-end and running-back receiving roles against the opponent’s coverage structure and personnel.
Coaching, pace and special teams
Account for fourth-down decisions, neutral pace, pass rate, kicking, punting, returns and field-position effects.
Travel, rest and weather
Verify body-clock travel, short weeks, altitude, surface, roof, wind and precipitation at the actual kickoff window.
Research contract status
What is known, and what remains unresolved
Moneyline, spread and total must preserve their book, number and price.
Questionable non-quarterbacks are weighted by role and recent snaps; major quarterback uncertainty still requires a specific backup projection.
Roof, surface and weather are separated so uncertainty stays visible.
Every qualified full-game moneyline, spread, and total forecast may enter the permanent Official Play record at a model-sized stake.
Sports Rounders NFL policy
Research first, release every qualified value.
The market favorite, public narrative, or injury list cannot manufacture an edge. Every fully priced, evidence-complete candidate may release when its lane clears.
Detroit Lions -22
Key-number movement through 3, 6, 7, 10 and 14 can materially change value.
65.5 points
Pace, neutral pass rate, explosive plays, red-zone efficiency, weather and injuries require a separate scoring forecast.
Live model
No release-count cap; the model sizes and permanently grades every qualified lane.
Matchup FAQ
Common questions about Detroit Lions vs. Arizona Cardinals
What is the Detroit Lions vs. Arizona Cardinals prediction?
Detroit Lions are favored by 22. This public forecast summarizes the current market and matchup evidence; it is not automatically an Official Play.
What is the spread for Detroit Lions vs. Arizona Cardinals?
Detroit Lions -22 is the current consensus spread. The exact number and price can vary by sportsbook and move before kickoff.
What is the total for Detroit Lions vs. Arizona Cardinals?
The current consensus total is 65.5 points.
Is this an official Sports Rounders pick?
No. An Official Play requires a complete evidence review, an independent model edge, an exact available price and publication before kickoff.